Counter-Irritation

The Theory and Practice of Counter-Irritation

supports. The author reviews at considerable length the history of the idea; but he does not wish to be esteemed an apostle of counterirritation : he expresses himself "more in sympathy with those who hold that 'the Devil himself, old Beelzebub, is nothing but a great Cantharid' (Baynard) than with those who would commend twelve consecutive applications of actual cautery for the cure of sciatic...

Skin irritation and corrosion.

Antipruritic Effect of Cold-induced and Transient Receptor Potential-agonist-induced Counter-irritation on Histaminergic Itch in Humans.

A frequent empirical observation is that cold-induced counter-irritation may attenuate itch. The aim of this randomized, single-blinded, exploratory study was to evaluate the counter-irritation effects of cold-stimulation and topical application of transient receptor potential TRPA1/M8-agonists (trans-cinnamaldehyde/L-menthol, respectively), on histamine-induced itch, wheals and neurogenic infl...

1 Subgroup 3 . Eye Irritation

Sensory irritation: risk assessment approaches.

Irritation of eyes and upper airways--sensory irritation--is commonly used as a parameter for setting occupational exposure limits and is a common complaint in occupants of non-industrial buildings. Sensory irritation occurs from stimulation of receptors on trigeminal nerves. In general, chemically reactive compounds are more potent than non-reactive congeners. Animal studies allow prediction o...